@import "https://fonts.googleapis.com/css2?family=DM+Sans:wght@400;500;600;700&family=Manrope:wght@400;500;600;700;800&display=swap";:root{color:#24324a;font-synthesis:none;--blue:#2563eb;--muted:#66758b;--border:#e4eaf2;--navy:#11233e;background:#f4f6fa;font-family:DM Sans,PingFang SC,Microsoft YaHei,sans-serif;font-size:16px;font-weight:400}*{box-sizing:border-box}body{margin:0}button,input,select{font:inherit}button,a{-webkit-tap-highlight-color:transparent}button{cursor:pointer}a{color:var(--blue);text-decoration:none}a:hover{text-decoration:underline}button:disabled{opacity:.45;cursor:default}button:focus-visible,a:focus-visible,input:focus-visible,select:focus-visible,summary:focus-visible{outline-offset:3px;outline:3px solid #73abff}button{border:0}h1,h2,h3,p{margin:0}button,select,input{font-size:.875rem}h1,h2,h3{font-family:Manrope,PingFang SC,Microsoft YaHei,sans-serif}h1{letter-spacing:-.03em;font-size:2rem;font-weight:800;line-height:1.5}h2{font-size:1.2rem;font-weight:750;line-height:1.6}h3{font-size:1rem;line-height:1.7}p{line-height:1.85}.app{min-height:100vh;display:flex}.sidebar{background:var(--navy);color:#bdc9db;z-index:30;flex-direction:column;width:244px;padding:30px 20px;display:flex;position:fixed;inset:0 auto 0 0}.brand{color:#fff;white-space:nowrap;align-items:center;gap:10px;margin:0 2px 55px;font-size:.95rem;font-weight:700;display:flex}.brand:hover{text-decoration:none}.brand small{letter-spacing:.11em;color:#99aecb;margin-top:5px;font-size:.6rem;font-weight:500;display:block}.brand-mark{color:#fff;font-family:Manrope,sans-serif;font-size:2.3rem;font-weight:800;line-height:1}.brand-mark span{color:#55c8bf}.nav-label,.small-label{color:#8295b1;letter-spacing:.08em;margin-bottom:16px;padding:0 13px;font-size:.7rem}.sidebar nav{flex-direction:column;gap:7px;display:flex}.sidebar nav button{color:#adbcd2;text-align:left;background:0 0;border-radius:7px;align-items:center;gap:13px;padding:14px;font-size:.94rem;display:flex}.sidebar nav button:hover{color:#fff;background:#1b3150}.sidebar nav button.selected{color:#fff;background:#274773}.nav-dot{background:#78c7ed;border-radius:50%;width:6px;height:6px;margin-left:auto}.sidebar-bottom{border-top:1px solid #2c3d55;margin-top:auto;padding:28px 13px 4px}.sidebar-bottom .small-label{padding:0;font-size:.65rem}.sidebar-bottom strong{color:#e0e9f5;margin:12px 0;font-family:Manrope;font-size:1.05rem;display:block}.sidebar-bottom p{color:#8fa3be;margin-bottom:20px;font-size:.83rem;line-height:1.9}.sidebar-bottom a{color:#b7d6ff;align-items:center;gap:8px;font-size:.82rem;display:flex}.workspace{width:calc(100% - 244px);min-width:0;margin-left:244px}.topbar{border-bottom:1px solid var(--border);color:#8490a1;background:#fff;justify-content:space-between;align-items:center;gap:18px;height:70px;padding:0 38px;font-size:.84rem;display:flex}.topbar b{color:#35465f;font-weight:500}.topbar a{color:#67768e;align-items:center;gap:9px;font-size:.78rem;display:flex}.menu-button{color:var(--navy);background:0 0;display:none}main{max-width:1600px;margin:auto;padding:32px 38px 0}.page-heading{justify-content:space-between;align-items:center;gap:25px;margin:0 0 28px;display:flex}.eyebrow{letter-spacing:.15em;color:#637992;margin-bottom:5px;font-size:.65rem;font-weight:700;display:block}.page-heading p{color:var(--muted);margin-top:8px;font-size:.875rem}.snapshot-label{color:#7b8ca4;white-space:nowrap;align-items:flex-start;gap:9px;font-size:.75rem;line-height:1.5;display:flex}.snapshot-label b{color:#40516b;margin-top:3px;font-size:.9rem;font-weight:600;display:block}.metrics{grid-template-columns:repeat(4,minmax(0,1fr));gap:16px;margin-bottom:26px;display:grid}.metric{border:1px solid var(--border);background:#fff;border-radius:9px;padding:22px 23px 20px;position:relative}.metric:first-child{background:var(--blue);border-color:var(--blue);color:#fff}.metric>span{color:#63718a;font-size:.82rem}.metric strong{font-variant-numeric:tabular-nums;letter-spacing:-.035em;margin:9px 0 7px;font-family:Manrope,sans-serif;font-size:2.2rem;font-weight:800;line-height:1.4;display:block}.metric small{color:#8390a4;font-size:.7rem;line-height:1.7}.metric:first-child>span,.metric:first-child small{color:#d7e7ff}.panel{border:1px solid var(--border);background:#fff;border-radius:9px;min-width:0;margin-bottom:24px;padding:25px 27px}.panel-head{justify-content:space-between;align-items:flex-start;gap:20px;margin-bottom:24px;display:flex}.section-number{color:#8a9bb0;letter-spacing:.1em;margin-bottom:4px;font-family:Manrope;font-size:.64rem;font-weight:700;display:block}.panel-head p{color:var(--muted);max-width:780px;margin-top:5px;font-size:.8rem}.panel-head label{max-width:280px}.export{color:#738198;border:1px solid var(--border);white-space:nowrap;background:#fff;border-radius:5px;align-items:center;gap:7px;padding:8px 11px;font-size:.75rem;display:flex}.export:hover{color:var(--blue);border-color:#9dc0fa}.chart-controls{flex-wrap:wrap;align-items:center;gap:18px;margin-bottom:16px;display:flex}.chart-controls>span{color:#7a8a9e;margin-left:auto;font-size:.75rem}label{color:var(--muted);flex-wrap:wrap;align-items:center;gap:10px;font-size:.8rem;display:flex}select{color:#43516a;background:#fff;border:1px solid #dbe3ec;border-radius:5px;max-width:100%;min-height:38px;padding:9px 12px}.toggle{background:#f1f4f8;border:1px solid #e7edf3;border-radius:6px;flex-shrink:0;gap:3px;padding:3px;display:inline-flex}.toggle button{color:#687990;white-space:nowrap;background:0 0;border-radius:4px;padding:8px 12px;font-size:.75rem}.toggle button.active{color:#225ece;background:#fff;box-shadow:0 1px 4px #14233a12}.chart{width:100%;min-width:0;font-size:.8rem}.chart.big{height:340px}.tooltip{border:1px solid var(--border);overflow-wrap:anywhere;background:#fff;border-radius:6px;max-width:300px;padding:12px 15px;font-size:.8rem;box-shadow:0 6px 20px #20334d15}.tooltip b{margin-bottom:6px;display:block}.tooltip div{align-items:center;gap:7px;line-height:1.8;display:flex}.tooltip i{border-radius:50%;width:7px;height:7px}.analysis{background:#f7f9fc;border-left:2px solid #cbdcf7;border-radius:0 5px 5px 0;margin:19px 0 0;padding:13px 17px}.analysis>div{align-items:flex-start;gap:13px;display:flex}.analysis>div+div{margin-top:7px}.analysis span{color:#6c84a3;white-space:nowrap;flex-shrink:0;font-size:.7rem;line-height:1.9}.analysis p{color:#52637c;font-size:.8rem;line-height:1.85}.two-col{grid-template-columns:1fr 1fr;gap:24px;min-width:0;display:grid}.two-col>.panel{height:calc(100% - 24px)}.donut-layout{justify-content:center;align-items:center;gap:4px;min-height:270px;display:flex}.donut{width:50%;height:230px}.legend-list{width:50%;padding-right:4px}.legend-list>div{color:#60718b;align-items:center;gap:8px;margin:18px 0;font-size:.75rem;display:flex}.legend-list i{border-radius:50%;flex-shrink:0;width:7px;height:7px}.legend-list span{flex:1}.legend-list b{color:#354963;font-weight:500}.caption{color:#7c8ba0;margin-top:15px;font-size:.78rem;line-height:1.8}.accessible-table{color:#738199;margin-top:13px;font-size:.75rem}.accessible-table summary{cursor:pointer;list-style-position:inside;display:list-item}.accessible-table[open] summary{margin-bottom:12px}.table-wrap{overflow:auto}table{border-collapse:collapse;text-align:left;width:100%;font-size:.83rem}th{color:#63748b;white-space:nowrap;background:#f5f7fa;font-weight:600}td,th{border-bottom:1px solid var(--border);padding:12px 14px;line-height:1.65}td{overflow-wrap:anywhere}.insight-grid{grid-template-columns:repeat(3,1fr);gap:28px;display:grid}.insight-grid article+article{border-left:1px solid var(--border);padding-left:28px}.insight-number{color:#a6b9d4;margin-bottom:9px;font-family:Manrope;font-size:1.4rem;font-weight:700;display:block}.insight-grid h3{margin-bottom:9px}.insight-grid p{color:#455d7c;font-size:.84rem}.insight-grid .muted{color:#8692a5;margin-top:12px;font-size:.77rem}.scope-bar{flex-wrap:wrap;justify-content:space-between;align-items:center;gap:20px;margin-bottom:20px;display:flex}.scope-bar>span{color:#7a8da8;font-size:.8rem}.heat-wrap{overflow:auto}.heatmap{border-collapse:separate;border-spacing:4px;min-width:850px;font-size:.7rem}.heatmap td{text-align:center;font-variant-numeric:tabular-nums;border:0;border-radius:3px;padding:13px 5px}.heatmap th{background:#fff;border:0;padding:7px 5px;font-size:.7rem;font-weight:500}.heatmap tbody th{white-space:normal;width:175px;max-width:175px}.heatmap thead th{text-align:center}.inline-facts{color:#6d809c;flex-wrap:wrap;gap:30px;margin-bottom:28px;font-size:.85rem;display:flex}.inline-facts b{color:#294c7c;margin-left:8px;font-size:1.15rem}.notice{color:#577195;background:#edf3fd;border:1px solid #d9e6fa;border-radius:6px;margin-bottom:24px;padding:14px 18px;font-size:.83rem;line-height:1.9}.people-layout{grid-template-columns:minmax(0,2fr) minmax(230px,1fr);gap:30px;display:grid}.people-note{background:#f9fbfd;border-radius:6px;align-self:start;padding:22px}.people-note>strong{color:#244a7e;margin:9px 0;font-family:Manrope;font-size:2.2rem;display:block}.people-note>p{color:#6e7e93;font-size:.83rem}.divider{border-bottom:1px solid var(--border);margin:20px 0}.people-note .analysis{background:0 0;border:0;padding:12px 0}.people-note .analysis>div{display:block}.people-note .analysis span{margin-bottom:6px;display:block}.source-cards{grid-template-columns:1fr 1fr;gap:25px;margin:25px 0;display:grid}.source-cards article{border:1px solid var(--border);border-radius:7px;padding:22px}.source-cards svg{color:#5779a8}.source-cards h3{margin:12px 0 8px}.source-cards p{color:#6d7d95;margin-bottom:15px;font-size:.85rem}.source-cards a{align-items:center;gap:6px;font-size:.82rem;display:flex}.lead-text{color:#566b86;font-size:.95rem}.method-steps{grid-template-columns:repeat(4,1fr);gap:20px;margin-bottom:28px;display:grid}.method-steps span{color:#9fbbdf;font-family:Manrope;font-size:1.5rem;font-weight:700}.method-steps h3{margin:10px 0}.method-steps p{color:#72839b;font-size:.81rem}.quality-grid{grid-template-columns:repeat(3,1fr);gap:14px;margin-bottom:22px;display:grid}.quality-grid>div{background:#f5f8fc;border-radius:5px;padding:16px 20px}.quality-grid span{color:#6f829c;font-size:.8rem}.quality-grid b{color:#25466f;margin-top:7px;font-family:Manrope;font-size:1.3rem;display:block}code{overflow-wrap:anywhere;background:#eef3f9;border-radius:3px;padding:2px 4px;font-size:.8rem}.hash{word-break:break-all}.panel>p{margin-top:16px}.search{border:1px solid var(--border);background:#f6f8fb;border-radius:6px;flex-wrap:nowrap;max-width:520px;margin-bottom:10px;padding:11px 14px}.search input{color:#354e70;background:0 0;border:0;outline:none;width:100%;font-size:.85rem}.sample-list article{border-bottom:1px solid var(--border);justify-content:space-between;gap:25px;padding:24px 0;display:flex}.sample-list article>div{flex:1}.sample-tag{color:#8398b3;font-size:.67rem}.sample-list h3{margin:7px 0;font-size:.95rem;line-height:1.75}.sample-list h3 a{color:#324b6d}.sample-list h3 svg{vertical-align:middle;margin-left:6px;display:inline-block}.sample-list p{color:#8291a8;font-size:.75rem}.sample-list dl{flex:0 0 210px;margin:10px 0 0;font-size:.75rem}.sample-list dl>div{justify-content:space-between;gap:18px;margin-bottom:9px;display:flex}.sample-list dt{color:#8290a5}.sample-list dd{color:#506785;margin:0}.loading,.empty{text-align:center;color:#7389a6;padding:70px 20px}.error{color:#9b4444;background:#fff0f0}footer{color:#91a0b4;flex-wrap:wrap;justify-content:space-between;gap:20px;padding:10px 0 28px;font-size:.7rem;display:flex}.backdrop{display:none}@media (width>=1700px){main{padding-top:40px}.chart.big{height:390px}}@media (width<=1200px){.sidebar{width:215px;padding:25px 14px}.workspace{width:calc(100% - 215px);margin-left:215px}main{padding:26px 24px 0}.topbar{padding:0 24px}.metric{padding:20px 16px}.metric strong{font-size:1.8rem}.panel{padding:22px}.two-col{grid-template-columns:1fr;gap:0}.panel-head .toggle button{padding:8px}.insight-grid{gap:20px}.insight-grid article+article{padding-left:20px}.donut-layout{max-width:600px;margin:auto}.donut{height:250px}.method-steps{grid-template-columns:repeat(2,1fr)}.no-gap-bottom{gap:20px}.people-layout{grid-template-columns:minmax(0,1.6fr) minmax(210px,1fr)}}@media (width<=850px){.sidebar{width:244px;transition:transform .18s;transform:translate(-100%)}.sidebar.open{transform:translate(0)}.workspace{width:100%;margin-left:0}.menu-button{display:block}.topbar>span{margin-right:auto}.topbar>a{font-size:.7rem}.backdrop{z-index:20;background:#10213966;display:block;position:fixed;inset:0}.metrics{grid-template-columns:repeat(2,1fr)}.insight-grid{grid-template-columns:1fr}.insight-grid article+article{border-left:0;border-top:1px solid var(--border);padding:20px 0 0}.people-layout,.source-cards{grid-template-columns:1fr}.page-heading{align-items:flex-start}.snapshot-label{margin-top:8px}}@media (width<=560px){main{padding:22px 14px 0}.topbar{height:60px;padding:0 16px}.topbar>a{display:none}.page-heading{display:block}.snapshot-label{margin-top:16px}.page-heading h1{font-size:1.7rem}.eyebrow{font-size:.56rem}.panel{padding:18px 12px}.panel-head{flex-wrap:wrap;gap:10px;margin-bottom:20px}.panel-head h2{font-size:1.05rem}.panel-head p{font-size:.75rem}.metric{padding:16px 14px}.metric strong{font-size:1.65rem}.metric>span{font-size:.74rem}.metric small{font-size:.65rem}.metrics{gap:10px}.chart.big{height:300px}.chart-controls{gap:14px}.chart-controls>span{margin-left:0}.analysis{padding:11px 12px}.analysis>div{display:block}.analysis span{margin-bottom:3px;display:block}.legend-list>div{gap:6px;font-size:.7rem}.donut{height:210px}.quality-grid{grid-template-columns:repeat(2,1fr)}.method-steps{gap:18px}.sample-list article{display:block}.sample-list dl{max-width:240px}.toggle button{padding:8px 10px}.scope-bar{gap:12px}.panel-head label{width:100%;max-width:none}.panel-head select{width:100%}.topbar{font-size:.8rem}footer{font-size:.65rem}td,th{padding:10px}.notice{padding:12px 14px}}@media (prefers-reduced-motion:reduce){*{scroll-behavior:auto!important;transition:none!important}}.panel-head p,.caption,.analysis p,.notice,.scope-bar>span,.toggle button,.metric>span,.insight-grid p,.insight-grid .muted,.people-note>p,.method-steps p,.legend-list>div,.sample-list p{font-size:.875rem}.metric small,.analysis span,.accessible-table,footer{font-size:.75rem}.cohort-note{color:#778ba5;margin:-6px 0 22px;font-size:.875rem;line-height:1.8}.domain-grid{grid-template-columns:repeat(auto-fit,minmax(170px,1fr));gap:12px;margin:18px 0;display:grid}.domain-grid button{text-align:left;cursor:pointer;color:#243751;background:#fff;border:1px solid #dce5ef;border-radius:10px;padding:18px}.domain-grid button.active,.domain-grid button:hover{background:#eff6ff;border-color:#2563eb}.domain-grid strong{margin:10px 0;font-size:25px;display:block}.domain-grid small{color:#64748b}.source-links{flex-wrap:wrap;gap:18px;margin-top:20px;display:flex}.snapshot-report-link{z-index:30;text-align:center;color:#fff;background:#173d4d;padding:10px 18px;font:14px/1.5 system-ui,sans-serif;text-decoration:none;display:block;position:relative}.snapshot-report-link:focus-visible{outline-offset:-3px;outline:3px solid #e5a425}.snapshot-populations{grid-template-columns:repeat(auto-fit,minmax(180px,1fr));gap:16px;margin:24px 0;display:grid}.snapshot-populations>div{background:#f8fbfc;border:1px solid #dce5eb;border-radius:6px;padding:20px}.snapshot-populations span{font-size:13px;display:block}.snapshot-populations strong{font-variant-numeric:tabular-nums;margin:10px 0;font-size:27px;display:block}.snapshot-populations small{color:#526777;font-size:11px}.snapshot-layout>main{width:100%;min-width:0}.snapshot-card{min-width:0}.snapshot-layout{grid-template-columns:220px minmax(0,1fr)}@media (width<=900px){.snapshot-layout{grid-template-columns:minmax(0,1fr)}}.snapshot-app label{color:#334b5f;font-size:14px}.snapshot-app .snapshot-table th{color:#192e40}.snapshot-card p,.snapshot-card h2{overflow-wrap:anywhere}.snapshot-reader-guide{color:#253e50;background:#fff;border:1px solid #dce5eb;border-radius:10px;margin:24px 0;padding:24px}.snapshot-reader-guide>h2{font-size:22px}.snapshot-reader-guide p{overflow-wrap:anywhere;margin:10px 0}.snapshot-source-intro{grid-template-columns:1fr 1fr;gap:24px;margin:20px 0;display:grid}.snapshot-source-intro>div{border-left:3px solid #87b5bd;padding-left:16px}.snapshot-reader-guide dt{margin-top:12px;font-weight:650}.snapshot-reader-guide dd{margin:4px 0 0 18px}.snapshot-reader-finding{background:#eaf5f4;border-radius:6px;padding:16px}.snapshot-source-audit{color:#445d70;font-size:13px}.snapshot-entry-tabs{flex-wrap:wrap;gap:10px;margin:20px 0;display:flex}.snapshot-analysis-layout{grid-template-columns:minmax(170px,220px) minmax(0,1fr);align-items:start;gap:20px;display:grid}.snapshot-analysis-index{background:#eaf0f4;border-radius:8px;max-height:calc(100vh - 36px);padding:16px;font-size:13px;position:sticky;top:18px;overflow:auto}.snapshot-analysis-index h2{margin:0 0 8px;font-size:18px}.snapshot-analysis-index p{font-size:12px}.snapshot-analysis-index a{overflow-wrap:anywhere;border-radius:5px;margin:5px 0;padding:10px;text-decoration:none;display:block}.snapshot-analysis-index a[aria-current]{background:#fff;border-left:3px solid #197a86;font-weight:650}.snapshot-analysis-index summary{white-space:normal}.snapshot-analysis-panel{min-width:0;scroll-margin-top:20px}.snapshot-analysis-panel>.snapshot-card{margin:16px 0}.snapshot-pagination{justify-content:space-between;align-items:center;gap:8px;font-size:13px;display:flex}.snapshot-method-brief{color:#344f60;border-top:1px solid #e1e8ed;margin:16px 0;padding-top:16px;font-size:14px}.snapshot-method-brief p{margin:6px 0}.snapshot-method-brief details{margin-top:8px}.snapshot-variant-name{color:#526777;margin:-8px 0 16px;font-size:13px}.snapshot-code-note{color:#526777;font-size:11px;font-weight:400;display:block}.snapshot-layout>nav{max-height:100vh;overflow-y:auto}.snapshot-controls select{width:100%;min-width:0;max-width:100%}.snapshot-controls label{flex:380px;min-width:0;max-width:100%}.snapshot-analysis-panel:focus,.snapshot-app h1:focus{outline:none}.snapshot-reader-guide li{margin:8px 0}.snapshot-reader-guide a{margin:0 4px}.snapshot-table th[scope=row]{position:static}@media (width<=1200px){.snapshot-analysis-layout{grid-template-columns:minmax(0,1fr)}.snapshot-analysis-index{display:none}}@media (width<=900px){.snapshot-layout>nav{z-index:20;background:#f4f7fa;max-height:none;position:sticky;top:0}.snapshot-source-intro{grid-template-columns:1fr;gap:14px}.snapshot-analysis-panel{scroll-margin-top:90px}}@media (width<=500px){.snapshot-reader-guide{padding:16px}.snapshot-pagination{font-size:11px}.snapshot-pagination button{padding:8px}.snapshot-entry-tabs button{flex:auto}.snapshot-reader-guide h2{font-size:20px}.snapshot-table caption{white-space:normal;min-width:240px}.snapshot-populations{grid-template-columns:1fr}}.publication-index{--index-ink:#172f46;--index-muted:#526579;--index-rule:#d5dfe6;--index-accent:#176b78;max-width:1080px;color:var(--index-ink);margin:auto;padding:64px 48px 40px;font-family:Noto Sans CJK SC,Microsoft YaHei,sans-serif}.publication-index .publication-name{color:var(--index-muted);margin:0 0 28px;font-size:16px}.publication-index h1{letter-spacing:0;margin:0 0 18px;font-family:Noto Serif CJK SC,Songti SC,serif;font-size:44px;font-weight:650;line-height:1.3}.publication-index .publication-intro{color:var(--index-muted);margin:0 0 40px;font-size:19px;line-height:1.8}.publication-list{border-top:2px solid var(--index-ink)}.publication-list>a{border-bottom:1px solid var(--index-rule);color:inherit;justify-content:space-between;align-items:center;gap:32px;padding:26px 4px;text-decoration:none;display:flex}.publication-list>a:hover{background:#edf3f6}.publication-list>a:focus-visible{outline:3px solid var(--index-accent);outline-offset:4px}.publication-list h2{letter-spacing:0;margin:8px 0;font-size:28px;font-weight:650;line-height:1.3}.publication-list p{max-width:640px;color:var(--index-muted);margin:0;font-size:16px;line-height:1.7}.publication-format{color:var(--index-muted);font-size:14px}.publication-action{color:var(--index-accent);white-space:nowrap;text-underline-offset:5px;font-size:15px;text-decoration:underline}.publication-build{grid-template-columns:auto 1fr;align-items:baseline;gap:4px 12px;margin:12px 0 14px;display:grid}.publication-build-label{color:var(--index-muted);font-size:13px}.publication-build time{font-variant-numeric:tabular-nums;color:var(--index-ink);font-size:19px;font-weight:650}.publication-build time small{color:var(--index-muted);white-space:nowrap;font-size:12px;font-weight:400}.publication-cutoff{color:var(--index-muted);grid-column:1/-1;font-size:13px;line-height:1.7}.publication-index footer{color:var(--index-muted);max-width:740px;margin-top:28px;font-size:13px;line-height:1.8}@media (width<=600px){.publication-index{padding:32px 22px}.publication-index h1{font-size:34px}.publication-index .publication-name{margin-bottom:24px;font-size:13px}.publication-index .publication-intro{margin-bottom:28px;font-size:17px}.publication-list>a{flex-direction:column;align-items:flex-start;gap:14px;padding:24px 0}.publication-list h2{font-size:26px}}@media (width<=760px){.publication-build{grid-template-columns:1fr}.publication-build time{font-size:18px}}